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1.
Sustainable Cities and Society ; : 104626, 2023.
Artículo en Inglés | ScienceDirect | ID: covidwho-2327199

RESUMEN

The COVID-19 pandemic has had a significant impact on metro commuting ridership. However, the exact magnitude and spatial and temporal characteristics of the impact remain unclear. In this study, we explored the impact of the COVID-19 outbreak on metro commuting ridership in Wuhan, where the novel virus was first reported. The results of interrupted time-series (ITS) analysis showed that metro commuting ridership sharply dropped in the short term under the impact of the outbreak in the epicenter, rebounded rapidly as the pandemic eased, and it returned to pre-pandemic levels in six months. Furthermore, there was a noticeable spatial heterogeneity in the rebound. Urban centers, especially employment centers, recovered faster than other areas. In addition, the number of residents, number of bus stops, number of enterprises around a metro station and being a transfer station had a positive effect on metro ridership, while street length, number of restaurants, and number of metro exits had a negative effect. These findings may help local governments and metro managers develop sustainable metro operations and infection prevention policies to better cope with the impact of the pandemic and beyond.

2.
Journal of Contingencies & Crisis Management ; 31(2):158-170, 2023.
Artículo en Inglés | Academic Search Complete | ID: covidwho-2316546

RESUMEN

The needs of volunteer community service providers (VCSPs), who are the main responders to community crises, have received significantly less attention for the contributions they have been making during the COVID‐19 crisis. A mixed‐method research framework was used in this study, which involved semi‐structured interviews with 13 NGOs and questionnaire responses from 430 VCSPs in Hubei, China to assess the VCSPs' personal needs based on Maslow's hierarchy of needs. It was found that the VCSPs had safety, love, belonging, self‐esteem, and self‐actualization personal needs, all of which were closely related to family, partners, organizations, society and the government. The discussions revealed that the more experienced VCSPs needed special attention and family support was extremely significant for VCSPs in crisis. Several recommendations to meet VCSPs' personal needs are proposed that could have valuable reference value for emergency managers when organizing and supporting VCSPs in contingencies. [ FROM AUTHOR] Copyright of Journal of Contingencies & Crisis Management is the property of Wiley-Blackwell and its content may not be copied or emailed to multiple sites or posted to a listserv without the copyright holder's express written permission. However, users may print, download, or email articles for individual use. This may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full . (Copyright applies to all s.)

3.
Cogn Sci ; 47(5): e13294, 2023 05.
Artículo en Inglés | MEDLINE | ID: covidwho-2316745

RESUMEN

People are known for good predictions in domains they have rich experience with, such as everyday statistics and intuitive physics. But how well can they predict for problems they lack experience with, such as the duration of an ongoing epidemic caused by a new virus? Amid the first wave of COVID-19 in China, we conducted an online diary study, asking each of over 400 participants to predict the remaining duration of the epidemic, once per day for 14 days. Participants' predictions reflected a reasonable use of publicly available information but were meanwhile biased, subject to the influence of negative affect and future time perspectives. Computational modeling revealed that participants neither relied on prior distributions of epidemic durations as in inferring everyday statistics, nor on mechanistic simulations of epidemic dynamics as in computing intuitive physics. Instead, with minimal experience, participants' predictions were best explained by similarity-based generalization of the temporal pattern of epidemic statistics. In two control experiments, we further confirmed that such cognitive algorithm is not specific to the epidemic scenario and that minimal and rich experience do lead to different prediction behaviors for the same observations. We conclude that people generalize patterns in recent history to predict the future under minimal experience.


Asunto(s)
COVID-19 , Humanos , COVID-19/epidemiología , Generalización Psicológica , Simulación por Computador , China/epidemiología
4.
Int J Clin Pract ; 2022: 4763953, 2022.
Artículo en Inglés | MEDLINE | ID: covidwho-2270119

RESUMEN

Objectives: The clinical and imaging features of asymptomatic carriers of severe acute respiratory syndrome coronavirus 2 and symptomatic COVID-19 patients. Methods: The clinical and chest computed tomography imaging data of 47 asymptomatic carriers and 36 symptomatic COVID-19 patients were derived. All patients underwent 4-6 CT scans over a period of 2-5 days. Results: The bulk of asymptomatic carriers who developed symptoms and most of the COVID-19 patients were older than 18 years of age with a decreased lymphocyte count, abnormal hepatic and renal function, and increased D-dimer and C-reactive protein. In the early stage, the pulmonary lesion involved mostly 1-2 lobes at the peripheral area in asymptomatic carriers but more than three lobes at both the central and peripheral areas in COVID-19 patients. In the progression stage, the lesion of asymptomatic carriers extended from the peripheral to the central area, and no significant difference was found in the lesion range compared with the symptomatic control group. In early improvement stage, the lesion was rapidly absorbed, and lesions were located primarily at the peripheral area in asymptomatic carriers; contrastingly, lesions were primarily located at both the central and peripheral areas in symptomatic patients. Asymptomatic carriers reflected a significantly shorter duration from disease onset to peak progression stage compared with the symptomatic. Conclusions: Asymptomatic carriers are a potential source of transmission and may become symptomatic COVID-19 patients despite indicating less severe pulmonary damage, earlier improvement, and better prognosis. Early isolation and intervention can eliminate such carriers as potential sources of transmission and improve their prognosis.


Asunto(s)
COVID-19 , Humanos , Estudios Retrospectivos , Pulmón/diagnóstico por imagen , SARS-CoV-2 , Proteína C-Reactiva
5.
Front Public Health ; 11: 1037846, 2023.
Artículo en Inglés | MEDLINE | ID: covidwho-2269834

RESUMEN

Intention: Global emergencies cause significant damage to lives, assets, and the economy. Therefore, the supply of relief goods is essential in emergency relief contexts, which is generally the function of non-government organizations (NGOs) as they have unique relief goods supply advantages. However, few studies have explored the influencing factors on NGO relief goods supply efficiency. To systematically explore the factors affecting supply efficiency, we aim to develop a supply chain model for simulating and providing policy suggestions. Method: Taking the 2020 Hubei COVID-19 as case study, this research developed a system dynamic (SD) model for the NGO relief supply system to evaluate and quantify the impact of factor changes on relief supplies. Conclusion: It was found that transportation and information delays aggravated the NGO emergency supply chain bullwhip effect and caused large supply fluctuations. The initial relief goods inventory was found to be a decisive factor in reducing shortages in disaster areas; however, government support was found to play only a limited role in reducing information and transportation delays. Value: This study enriches NGO emergency supply chain literature and provides suggestions for guiding NGO relief goods supplies in the future.


Asunto(s)
COVID-19 , Desastres , Humanos , Organizaciones
6.
Mol Biol Cell ; 33(14): ar147, 2022 Dec 01.
Artículo en Inglés | MEDLINE | ID: covidwho-2269835

RESUMEN

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) utilizes its Spike (S) glycoprotein to bind to the angiotensin-converting enzyme 2 (ACE2) receptor for cellular entry. ACE2 is a critical negative regulator of the renin-angiotensin system and plays a protective role in preventing tissue injury. Expression of ACE2 has been shown to decrease upon infection by SARS-CoV. However, whether SARS-CoV-2 down-regulates ACE2 and the underlying mechanism and biological impact of this down-regulation have not been well defined. Here we show that the SARS-CoV-2 infection down-regulates ACE2 in vivo in an animal model, and in cultured cells in vitro, by inducing clathrin- and AP2-dependent endocytosis, leading to its degradation in the lysosome. SARS-CoV-2 S-treated cells and ACE2 knockdown cells exhibit similar alterations in downstream gene expression, with a pattern indicative of activated cytokine signaling that is associated with respiratory distress and inflammatory diseases often observed in COVID-19 patients. Finally, we have identified a soluble ACE2 fragment with a stronger binding to SARS-CoV-2 S that can efficiently block ACE2 down-regulation and viral infection. Thus, our study suggests that ACE2 down-regulation represents an important mechanism underlying SARS-CoV-2-associated pathology, and blocking this process could be a promising therapeutic strategy.


Asunto(s)
Enzima Convertidora de Angiotensina 2 , COVID-19 , Animales , SARS-CoV-2 , Peptidil-Dipeptidasa A/genética , Peptidil-Dipeptidasa A/metabolismo , Lisosomas/metabolismo , Unión Proteica
7.
Environmental Hazards ; : 1-16, 2023.
Artículo en Inglés | Taylor & Francis | ID: covidwho-2212599
8.
J Vis Exp ; (187)2022 09 07.
Artículo en Inglés | MEDLINE | ID: covidwho-2217149

RESUMEN

Virus infections have a major impact on society; most methods of detection have difficulties in determining whether a detected virus is infectious, causing delays in treatment and further spread of the virus. Developing new sensors that can inform on the infectability of clinical or environmental samples will meet this unmet challenge. However, very few methods can obtain sensing molecules that can recognize an intact infectious virus and differentiate it from the same virus that has been rendered non-infectious by disinfection methods. Here, we describe a protocol to select aptamers that can distinguish infectious viruses vs non-infectious viruses using systematic evolution of ligands by exponential enrichment (SELEX). We take advantage of two features of SELEX. First, SELEX can be tailor-made to remove competing targets, such as non-infectious viruses or other similar viruses, using counter selection. Additionally, the whole virus can be used as the target for SELEX, instead of, for example, a viral surface protein. Whole virus SELEX allows for the selection of aptamers that bind specifically to the native state of the virus, without the need to disrupt of the virus. This method thus allows recognition agents to be obtained based on functional differences in the surface of pathogens, which do not need to be known in advance.


Asunto(s)
Aptámeros de Nucleótidos , Virosis , Virus , Aptámeros de Nucleótidos/metabolismo , Humanos , Ligandos , Proteínas de la Membrana , Técnica SELEX de Producción de Aptámeros/métodos , Virus/metabolismo
9.
Landsc Urban Plan ; 233: 104690, 2023 May.
Artículo en Inglés | MEDLINE | ID: covidwho-2181284

RESUMEN

Non-pharmaceutical interventions (NPIs) remain some of the most effective measures for coping with the ever-changing coronavirus disease 2019 (COVID-19) pandemic. Pandemic fatigue, which manifests as the declined willingness to follow the recommended protective behaviors (e.g., keeping social distance policies, wearing masks), has commanded increasing attention from researchers and policymakers after the prolonged NPIs and COVID-19 worldwide. However, long-term changes in pandemic fatigue are not well understood, especially amidst the ever-changing pandemic landscape. Built environment factors have been shown to positively affect mental and physical health, but it is still unclear whether built environments can moderate pandemic fatigue. In this study, we used Google mobility data to investigate longitudinal trends of pandemic fatigue in social distance since the onset of NPIs enforcement in the United States. The results indicated that pandemic fatigue continuously worsened over nearly two years of NPIs implementation, and a sharp increase occurred after the vaccination program began. Additionally, we detected a significant moderation effect of greenspace and urbanicity levels on pandemic fatigue. People living in areas with high levels of greenness or urbanicity experienced lower levels of pandemic fatigue. These findings not only shed new light on the effects of greenness and urbanicity on COVID-19 pandemic fatigue, but also provide evidence for developing more tailored and effective strategies to cope with pandemic fatigue.

10.
Bio Protoc ; 12(21)2022 Nov 05.
Artículo en Inglés | MEDLINE | ID: covidwho-2146018

RESUMEN

Aptamers have been selected with strong affinity and high selectivity for a wide range of targets, as recently highlighted by the development of aptamer-based sensors that can differentiate infectious from non-infectious viruses, including human adenovirus and SARS-CoV-2. Accurate determination of the binding affinity between the DNA aptamers and their viral targets is the first step to understanding the molecular recognition of viral particles and the potential uses of aptamers in various diagnostics and therapeutic applications. Here, we describe protocols to obtain the binding curve of the DNA aptamers to SARS-CoV-2 using Enzyme-Linked Oligonucleotide Assay (ELONA) and MicroScale Thermophoresis (MST). These methods allow for the determination of the binding affinity of the aptamer to the infectious SARS-CoV-2 and the selectivity of this aptamer against the same SARS-CoV-2 that has been rendered non-infectious by UV inactivation, and other viruses. Compared to other techniques like Electrophoretic Mobility Shift Assay (EMSA), Surface Plasmon Resonance (SPR), and Isothermal Titration Calorimetry (ITC), these methods have advantages for working with larger particles like viruses and with samples that require biosafety level 2 facilities.

11.
Front Public Health ; 10: 925475, 2022.
Artículo en Inglés | MEDLINE | ID: covidwho-2121936

RESUMEN

Background: Autism spectrum disorders (ASD) are heterogeneous neurodevelopmental conditions that affect people worldwide. Early diagnosis and clinical support help achieve good outcomes. However, medical system structure and restricted resource availability create challenges that increase the risk of poor outcomes. Understanding the research progress of childhood ASD in recent years, based on clinical literature reports, can give relevant researchers and rehabilitation therapists more resonable research guides. Objective: This bibliometric study aimed to summarize themes and trends in research on childhood ASD and to suggest directions for future enquiry. Methods: Citations were downloaded from the Web of Science Core Collection database on childhood ASD published from 1 January 2012, to 31 December 2021. The retrieved information was analyzed using CiteSpace.5.8. R3, and VOS viewer. Results: A total of 7,611 papers were published across 103 areas. The United States was the leading source of publications. The clusters that have continued into 2020 include coronavirus disease 2019, gut microbiota, and physical activity, which represent key research topics. Keywords with frequency spikes during 2018-2021 were "disabilities monitoring network," "United States," and "caregiver." Conclusions: The Autism and Developmental Disabilities Monitoring Network in the United States can be used as a reference for relevant workers worldwide. An intelligent medical assistant system is being developed. Further studies are required to elucidate challenges associated with caring for a child with ASD.


Asunto(s)
Trastorno del Espectro Autista , COVID-19 , Microbioma Gastrointestinal , Bibliometría , COVID-19/epidemiología , Niño , Bases de Datos Factuales , Humanos , Estados Unidos
12.
Frontiers in public health ; 10, 2022.
Artículo en Inglés | EuropePMC | ID: covidwho-2034541

RESUMEN

Background Autism spectrum disorders (ASD) are heterogeneous neurodevelopmental conditions that affect people worldwide. Early diagnosis and clinical support help achieve good outcomes. However, medical system structure and restricted resource availability create challenges that increase the risk of poor outcomes. Understanding the research progress of childhood ASD in recent years, based on clinical literature reports, can give relevant researchers and rehabilitation therapists more resonable research guides. Objective This bibliometric study aimed to summarize themes and trends in research on childhood ASD and to suggest directions for future enquiry. Methods Citations were downloaded from the Web of Science Core Collection database on childhood ASD published from 1 January 2012, to 31 December 2021. The retrieved information was analyzed using CiteSpace.5.8. R3, and VOS viewer. Results A total of 7,611 papers were published across 103 areas. The United States was the leading source of publications. The clusters that have continued into 2020 include coronavirus disease 2019, gut microbiota, and physical activity, which represent key research topics. Keywords with frequency spikes during 2018–2021 were “disabilities monitoring network,” “United States,” and “caregiver.” Conclusions The Autism and Developmental Disabilities Monitoring Network in the United States can be used as a reference for relevant workers worldwide. An intelligent medical assistant system is being developed. Further studies are required to elucidate challenges associated with caring for a child with ASD.

13.
Landscape and urban planning ; 2022.
Artículo en Inglés | EuropePMC | ID: covidwho-2034046

RESUMEN

The coronavirus pandemic is an ongoing global crisis that has profoundly harmed public health. Although studies found exposure to green spaces can provide multiple health benefits, the relationship between exposure to green spaces and the SARS-CoV-2 infection rate is unclear. This is a critical knowledge gap for research and practice. In this study, we examined the relationship between total green space, seven types of green space, and a year of SARS-CoV-2 infection data across 3,108 counties in the contiguous United States, after controlling for spatial autocorrelation and multiple types of covariates. First, we examined the association between total green space and SARS-CoV-2 infection rate. Next, we examined the association between different types of green space and SARS-CoV-2 infection rate. Then, we examined forest–infection rate association across five time periods and five urbanicity levels. Lastly, we examined the association between infection rate and population-weighted exposure to forest at varying buffer distances (100m to 4km). We found that total green space was negative associated with the SARS-CoV-2 infection rate. Furthermore, two forest variables (forest outside park and forest inside park) had the strongest negative association with the infection rate, while open space variables had mixed associations with the infection rate. Forest outside park was more effective than forest inside park. The optimal buffer distances associated with lowest infection rate are within 1,200m for forest outside park and within 600m for forest inside park. Altogether, the findings suggest that green spaces, especially nearby forest, may significantly mitigate risk of SARS-CoV-2 infection.

14.
Evid Based Complement Alternat Med ; 2022: 7784148, 2022.
Artículo en Inglés | MEDLINE | ID: covidwho-2020534

RESUMEN

The acute lung injury (ALI) causes severe pulmonary diseases, leading to a high mortality rate. The Renshen and Chishao have protective and anti-inflammatory effects against the ALI. To explore the protective effects of the Renshen Chishao (RC) decoction against the ALI, we established the lipopolysaccharide-indued ALI model and randomly divided the mice into seven groups: control group, ALI group, high-dose RC group, middle-dose RC group, low-dose RC group, middle-dose RC group + CXCR2 antagonist group, and ALI + CXCR2 antagonist group. We estimated the lung injury by the hematoxylin and eosin staining, the neutrophil extracellular traps (NETs) formations by the immunofluorescence colocalization and enzyme-linked immunosorbent assay (ELISA), and the CXCR2/CXCL2 pathway by the flow cytometry, ELISA, and real-time polymerase chain reaction. We conducted the high-throughput sequencing and enrichment analyses to explore the potential mechanisms. The results showed that the RC decoction pathologically ameliorated the lipopolysaccharide-induced lung injury and inflammatory response but failed to reduce the circulating and lung tissue NETs formation and the blood neutrophil percent. The high-dose RC decoction increased the plasma CXCL2 level, but the RC decoction had no effects on the neutrophilic CXCR2 levels. Under the inhibition of the CXCR2, the middle-dose RC decoction still decreased the lung injury score but as yet had unobvious influence on the NETs formation. Other potential mechanisms of the RC decoction against the ALI involved the pathways of ribosome and coronavirus disease 2019 (COVID-19); the target genes of inflammatory factors, such as Ccl17, Cxcl17, Cd163, Cxcr5, and Il31ra, and lncRNAs; and the regulations of the respiratory cilia. In conclusion, the RC decoction pathologically ameliorated the lipopolysaccharide-induced lung inflammatory injury via upregulating the CXCL2/CXCR2 pathway but could not reduce the circulating or lung tissue NETs formation.

15.
Sci Total Environ ; 851(Pt 2): 158333, 2022 Dec 10.
Artículo en Inglés | MEDLINE | ID: covidwho-2004488

RESUMEN

The COVID-19 pandemic has caused a huge loss of human life globally. However, few studies investigated the link between exposure to green space and risk of COVID-19 mortality rate, while also distinguishing the effects of various types of green space, considering the spatial distribution of human population and green space, and identifying the optimal buffer distances of nearby green space. It is critical and pressing to fill these significant knowledge gaps to protect and promote billions of people's health and life across the world. This study adopted a negative binomial generalized linear mixed-effects model to examine the association between the ratios of various types of green space, population-weighted exposure to those various types of green space, and COVID-19 mortality rates across 3025 counties in the USA, adjusted for sociodemographic, pre-existing chronic disease, policy and regulation, behavioral, and environmental factors. The findings show that greater exposure to forest was associated with lower COVID-19 mortality rates, while developed open space had mixed associations with COVID-19 mortality rates. Forest outside park had the largest effect size across all buffer distances, followed by forest inside park. The optimal exposure buffer distance was 1 km for forest outside park, with per one-unit of increase in exposure associated with a 9.9 % decrease in COVID-19 mortality rates (95 % confidence interval (CI): 6.9 %-12.8 %). The optimal exposure buffer distance of forest inside park was 400 m, with per one-unit of increase in exposure associated with a 4.7 % decrease in mortality rates (95 % CI: 2.4 %-6.9 %). The results suggest that greater exposure to green spaces, especially to nearby forests, may mitigate the risk of COVID-19 mortality. Although findings of an ecological study cannot be directly used to guide medical interventions, this study may pave a critical new way for future research and practice across multiple disciplines.


Asunto(s)
COVID-19 , Parques Recreativos , Humanos , Estados Unidos/epidemiología , Pandemias
16.
Journal of Contingencies and Crisis Management ; n/a(n/a), 2022.
Artículo en Inglés | Wiley | ID: covidwho-1937866

RESUMEN

The needs of volunteer community service providers (VCSPs), who are the main responders to community crises, have received significantly less attention for the contributions they have been making during the COVID-19 crisis. A mixed-method research framework was used in this study, which involved semi-structured interviews with 13 NGOs and questionnaire responses from 430 VCSPs in Hubei, China to assess the VCSPs' personal needs based on Maslow's hierarchy of needs. It was found that the VCSPs had safety, love, belonging, self-esteem, and self-actualization personal needs, all of which were closely related to family, partners, organizations, society and the government. The discussions revealed that the more experienced VCSPs needed special attention and family support was extremely significant for VCSPs in crisis. Several recommendations to meet VCSPs' personal needs are proposed that could have valuable reference value for emergency managers when organizing and supporting VCSPs in contingencies.

17.
Pharmaceuticals (Basel) ; 15(7)2022 Jun 26.
Artículo en Inglés | MEDLINE | ID: covidwho-1911507

RESUMEN

The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) caused a global pandemic in 2019-coronavirus disease (COVID-19). More and more Western medicine (WM) and Chinese herbal medicine (CHM) treatments have been used to treat COVID-19 patients, especially among Asian populations. However, the interactions between WM and CHM have not been studied. This study aims at using the network pharmacology approach to explore the potential complementary effects among commonly used CHM and WM in a clinical setting from a biomolecular perspective. Three well-published and widely used CHM formulas (National Research Institute of Chinese Medicine 101 (NRICM101), Qing-Fei-Pai-Du-Tang (QFPDT), Hua-Shi-Bai-Du-Formula (HSBDF)) and six categories of WM (Dexamethasone, Janus kinase inhibitors (JAKi), Anti-Interleukin-6 (Anti-IL6), anticoagulants, non-vitamin K antagonist oral anticoagulants (NOAC), and Aspirin) were included in the network pharmacology analysis. The target proteins on which these CHM and WM had direct effects were acquired from the STITCH database, and the potential molecular pathways were found in the REACTOME database. The COVID-19-related target proteins were obtained from the TTD database. For the three CHM formulas, QFPDT covered the most proteins (714), and 27 of them were COVID-19-related, while HSBDF and NRICM101 covered 624 (24 COVID-19-related) and 568 (25 COVID-19-related) proteins, respectively. On the other hand, WM covered COVID-19-related proteins more precisely and seemed different from CHM. The network pharmacology showed CHM formulas affected several inflammation-related proteins for COVID-19, including IL-10, TNF-α, IL-6, TLR3, and IL-8, in which Dexamethasone and Aspirin covered only IL-10 and TNF-α. JAK and IL-6 receptors were only inhibited by WM. The molecular pathways covered by CHM and WM also seemed mutually exclusive. WM had advantages in cytokine signaling, while CHM had an add-on effect on innate and adaptive immunity, including neutrophil regulation. WM and CHM could be used together to strengthen the anti-inflammation effects for COVID-19 from different pathways, and the combination of WM and CHM may achieve more promising results. These findings warrant further clinical studies about CHM and WM use for COVID-19 and other diseases.

18.
Mol Psychiatry ; 27(8): 3214-3222, 2022 Aug.
Artículo en Inglés | MEDLINE | ID: covidwho-1878516

RESUMEN

Infectious disease epidemics have become more frequent and more complex during the 21st century, posing a health threat to the general public and leading to psychological symptoms. The current study was designed to investigate the prevalence of and risk factors associated with depression, anxiety and insomnia symptoms during epidemic outbreaks, including COVID-19. We systematically searched the PubMed, Embase, Web of Science, OVID, Medline, Cochrane databases, bioRxiv and medRxiv to identify studies that reported the prevalence of depression, anxiety or insomnia during infectious disease epidemics, up to August 14th, 2020. Prevalence of mental symptoms among different populations including the general public, health workers, university students, older adults, infected patients, survivors of infection, and pregnant women across all types of epidemics was pooled. In addition, prevalence of mental symptoms during COVID-19 was estimated by time using meta-regression analysis. A total of 17,506 papers were initially retrieved, and a final of 283 studies met the inclusion criteria, representing a total of 948,882 individuals. The pooled prevalence of depression ranged from 23.1%, 95% confidential intervals (95% CI: [13.9-32.2]) in survivors to 43.3% (95% CI: [27.1-59.6]) in university students, the pooled prevalence of anxiety ranged from 25.0% (95% CI: [12.0-38.0]) in older adults to 43.3% (95% CI: [23.3-63.3]) in pregnant women, and insomnia symptoms ranged from 29.7% (95% CI: [24.4-34.9]) in the general public to 58.4% (95% CI: [28.1-88.6]) in university students. Prevalence of moderate-to-severe mental symptoms was lower but had substantial variation across different populations. The prevalence of mental problems increased over time during the COVID-19 pandemic among the general public, health workers and university students, and decreased among infected patients. Factors associated with increased prevalence for all three mental health symptoms included female sex, and having physical disorders, psychiatric disorders, COVID infection, colleagues or family members infected, experience of frontline work, close contact with infected patients, high exposure risk, quarantine experience and high concern about epidemics. Frequent exercise and good social support were associated with lower risk for these three mental symptoms. In conclusion, mental symptoms are common during epidemics with substantial variation across populations. The population-specific psychological crisis management are needed to decrease the burden of psychological problem and improve the mental wellbeing during epidemic.


Asunto(s)
COVID-19 , Enfermedades Transmisibles , Trastornos del Inicio y del Mantenimiento del Sueño , Embarazo , Femenino , Humanos , Anciano , COVID-19/epidemiología , Pandemias , Trastornos del Inicio y del Mantenimiento del Sueño/epidemiología , Prevalencia , Depresión/epidemiología , Depresión/etiología , SARS-CoV-2 , Ansiedad/epidemiología , Ansiedad/etiología , Factores de Riesgo , Enfermedades Transmisibles/epidemiología
19.
J Affect Disord ; 309: 368-374, 2022 07 15.
Artículo en Inglés | MEDLINE | ID: covidwho-1804391

RESUMEN

OBJECTIVES: While there have been some studies examining the post-traumatic growth (PTG) responses to the COVID-19 pandemic, few have been longitudinal studies exploring the changes over time or examining the underlying psychological PTG mechanisms. This study examined whether baseline perceived emotional intelligence (EI) predicted PTG through self-esteem and emotional regulation (ER) in a five-month follow-up study conducted on Chinese adolescents during the COVID-19 pandemic. METHODS: Validated measures were completed by 2090 participants, which assessed both the perceived EI and the PTG 1 month after a nationwide lockdown in China, with 1609 of these participating in the follow-up five months later. Structural equation models (SEM) were then used to explore the paths between the variables. RESULTS: As hypothesized, the follow-up survey found that the baseline perceived EI predicted PTG, ER, and self-esteem outcomes. The SEM analyses also revealed that self-esteem and ER significantly mediated the association between EI and PTG. LIMITATIONS: Studies of three or more waves may be more suitable for longitudinal mediation analyses. Self-assessment reports may have subjective effects. CONCLUSIONS: It was concluded that perceived EI might improve PTG in adolescents following the COVID-19 pandemic, and self-esteem and ER program training could be helpful in promoting PTG.


Asunto(s)
COVID-19 , Crecimiento Psicológico Postraumático , Adolescente , Control de Enfermedades Transmisibles , Inteligencia Emocional , Estudios de Seguimiento , Humanos , Pandemias , Estudios Prospectivos
20.
Tunnelling and Underground Space Technology ; : 104528, 2022.
Artículo en Inglés | ScienceDirect | ID: covidwho-1799682

RESUMEN

The metro (or underground railways) has become a backbone in the transit systems of many cities. It has numerous externalities, such as ameliorating traffic congestion and enhancing nearby property prices. Previous studies extensively focused on the relationship between metro accessibility and property prices and obtained various interesting findings and enriched practical implications. However, this relationship in the era of the coronavirus disease 2019 (COVID-19) and other epidemic shocks has not been investigated. Based on a unique property transaction dataset (including tens of thousands of transactions stretching from 2018 to 2020) in Chengdu, China, this study develops a battery of hedonic pricing models and difference-in-differences models to decipher the time-varying relationship between metro accessibility and residential property prices. The results show that the implicit price of metro accessibility modestly decreases in COVID-19, which can be explained by the declining role of the metro. Specifically, the price elasticity of distance to the metro is −0.024 before COVID-19, but it turns to −0.018 during the pandemic. The relative price of properties within 500 m from metro stations to those farther away (500 m − 3 km) decreases by 15.4% during the pandemic. Additionally, COVID-19 does not jeopardize property prices in Chengdu. The plausibility and robustness of the core findings have been confirmed through alternative treatment groups, alternative model specifications, and placebo tests.

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